Methicillin-Resistant Staphylococcus aureus and Vancomycin: Minimum Inhibitory Concentration Matters
نویسندگان
چکیده
منابع مشابه
Accessory Gene Regulator Polymorphism and Vancomycin Minimum Inhibitory Concentration in Methicillin-Resistant Staphylococcus aureus
BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with a vancomycin minimum inhibitory concentration (MIC) of 2 µg/mL presents a high rate of therapeutic failure in response to vancomycin. In addition, polymorphism in accessory gene regulator (agr) is associated with vancomycin therapeutic effects. The association between agr polymorphism and vancomycin MICs was investiga...
متن کاملInfluence of vancomycin minimum inhibitory concentration on the treatment of methicillin-resistant Staphylococcus aureus bacteremia.
BACKGROUND Vancomycin treatment failure in methicillin-resistant Staphylococcus aureus (MRSA) bacteremia is not uncommon, even when MRSA is susceptible to vancomycin. The aim of our study was to evaluate whether vancomycin minimum inhibitory concentration has any influence on the mortality associated with MRSA bacteremia. METHODS A total of 414 episodes of MRSA bacteremia were prospectively f...
متن کاملDaptomycin or vancomycin for methicillin-resistant Staphylococcus aureus with a vancomycin minimum inhibitory concentration >1 μg/L.
Correspondence Daptomycin or Vancomycin for Methicillin-Resistant Staphylococcus aureus with a Vancomycin Minimum Inhibitory Concentration .1 mg/L To the Editor—We commend Moore et al for their study comparing the effectiveness and safety of vancomycin and daptomycin in the treatment of bacteremia due to methicillin-resistant Staphylococcus aureus (MRSA) with a vancomycin minimal inhibitory con...
متن کاملPrevalence of Vancomycin Resistance in Methicillin-Resistant Staphylococcus Aureus
Background & Aims: Staphylococcus aureus is one of the most common pathogens in nosocomial infections. Vancomycin is the most important therapeutic drug of choice for treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) strains. Therefore, vancomycin-resistant Staphylococcus aureus (VRSA) or vancomycin-intermediate Staphylococcus aureus (VISA) strains are warning...
متن کاملVancomycin minimum inhibitory concentration in methicillin-susceptible Staphylococcus aureus and mortality: more than handwaving?
TO THE EDITOR—We read with great interest the study by Cervera and colleagues on the effect of vancomycin minimum inhibitory concentration (van-MIC) on clinical outcome in 93 patients with leftsided infective endocarditis due to methicillin-susceptible Staphylococcus aureus (MSSA) [1]. However, various questions remain unanswered. The 3-fold higher mortality in the group of patients with a van-...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2012
ISSN: 1537-6591,1058-4838
DOI: 10.1093/cid/cir932